HIPECPIPACCytoreductive Surgery (CRS)Whipple’s ProcedureTotal Gastrectomy D2Minimally Invasive OesophagectomyColorectal Resection + TMELiver Metastases ResectionOvarian Cancer Debulking + HIPECRetroperitoneal Tumour ResectionPelvic ExenterationAppendix Cancer & PMP Surgery
Peritoneal CancerPancreatic CancerGastric (Stomach) CancerColorectal CancerOvarian CancerOesophageal CancerAppendix Cancer & PMPLiver Cancer & MetastasesGallbladder & Bile Duct CancerSmall Bowel CancerSoft Tissue SarcomaRare Abdominal Cancers📍 WhatsApp Us
HIPEC
PIPAC
Cytoreductive Surgery
Whipple’s Procedure
Total Gastrectomy D2
Minimally Invasive Oesophagectomy
Colorectal Cancer TME
Liver Metastases Resection
Ovarian Cancer Debulking
Retroperitoneal Tumour Resection
Pelvic Exenteration
Appendix Cancer & PMP
What Is Peritoneal Cancer?
Peritoneal cancer refers to malignancies that develop on or spread to the peritoneum, the thin layer of tissue lining the abdominal cavity and covering the abdominal organs. It can arise primarily (peritoneal mesothelioma, primary peritoneal carcinoma) or more commonly as a secondary spread (peritoneal carcinomatosis) from cancers of the ovary, colon, stomach, appendix, or pancreas.
For a long time, peritoneal spread was considered a death sentence with only palliative systemic chemotherapy offered. Today, for carefully selected patients, a combination of cytoreductive surgery (CRS) to remove all visible disease and HIPEC, heated chemotherapy delivered directly into the abdominal cavity, offers genuine curative potential with excellent long-term outcomes.
I trained specifically in peritoneal surface oncology at Medizinische Hochschule Hannover, Germany, under pioneers of HIPEC and PIPAC. The techniques I practise here in Hyderabad are identical to what is offered at the world’s leading centres, your distance from Europe should never be a barrier to world-class care.
At a Glance
Recognising Peritoneal Cancer
Symptoms are often vague and mimic other abdominal conditions, early diagnosis requires a high index of suspicion, especially in patients with a previous abdominal cancer.
Progressive swelling due to ascites (fluid accumulation) in the peritoneal cavity.
Feeling full quickly, nausea, and unexplained loss of appetite or weight.
Diffuse or localised pain, often dull and persistent, worsening over weeks.
Constipation, diarrhoea, or obstruction as tumour deposits press on the bowel.
Systemic effects of cancer causing unexplained, persistent tiredness.
Peritoneal deposits discovered during staging CT for another primary cancer.
How I Treat Peritoneal Cancer
The treatment approach depends on the primary cancer site, PCI score, and the patient’s overall fitness. In my practice, I first stage every patient with a diagnostic laparoscopy to accurately assess PCI before committing to open surgery, this avoids unnecessary large operations for patients who would not benefit.
For patients with resectable disease (typically PCI ≤ 20), CRS involves meticulously removing all peritoneal deposits, often requiring removal of affected bowel segments, omentum, spleen, or parts of other organs. This is immediately followed by HIPEC: heated cisplatin or oxaliplatin circulated in the abdomen for 90 minutes to eradicate microscopic residual disease.
For patients who are not immediately eligible for CRS/HIPEC, or who have progressed after systemic chemotherapy, PIPAC offers a minimally invasive laparoscopic option delivering chemotherapy as a pressurised aerosol into the abdominal cavity, repeated every 6 weeks with minimal systemic toxicity.
Complete surgical removal of all visible peritoneal disease, the foundation of curative peritoneal cancer treatment.
Heated intraperitoneal chemotherapy delivered immediately after CRS to eradicate microscopic disease.
Minimally invasive laparoscopic aerosol chemotherapy for patients not eligible for open CRS+HIPEC.
Expertise You Can Trust
Dr. Mohammed Imaduddin brings internationally trained surgical skills and a patient-first philosophy to every case.
Frequently Asked Questions
The most common questions I receive from patients and families facing a peritoneal cancer diagnosis.
Is peritoneal cancer always terminal?
How do I know if I am eligible for HIPEC?
What is the difference between HIPEC and PIPAC?
How long is recovery after CRS+HIPEC?
Can PIPAC be done in Hyderabad?
Ready to Discuss Your Case?
Every cancer journey is different. I offer a detailed, unhurried consultation to help you understand your options and make informed decisions.